Kewl Article on Pre-Loading and "E"-Comments Please

[blackjack]

Here is an article that my friend emailed me, sounds pretty interesting....Any comments/corrections/disputes are welcome:

Allaying imbalance in your Neurochemistry

There is some evidence that taking Melatonin can prep your neurochemistry

before MDMA or reboot your brain after taking MDMA. There is also some

practice of taking ONE SSRI (Selective Serotonin Reuptake Inhibitor, e.g.

Prozac, Zoloft, or Paxil) the morning after, for that's when the damage

hits - the two days after ingestion. It stops the effects of MDMA in its

tracks, but should prevent any neurotransmitter damage. But taking too much

can result in a hypertensive crisis and a near fatal response. You're

playing with fire, is it REALLY worth it?

Pre-loading is an attempt to enhance the good effects of MDMA and reduce the

negative ones. These vitamins and amino acids are all available from health

food shops. Many people who have tried pre-loading say that it helps a

great deal. The most important one to take is 5-HTP which is a precursor of

serotonin. But 5HTP can make the experience so intense as to be more

potentially damaging to vulnerable individuals.

Pre-loading with precursors of the neurotransmitters depleted by MDMA will

give you a better roll and ease your comedown.

Dr. Tom Oth writes (in the MDMA Clearinghouse Forum):

1. 200-500mg 5-hydroxytryptophan (5-HTP)

2. 500-1000mg tyrosine

3. 500-1500mg DLPA

4. 2 grams glutamine

5. 1 gram of vitamin C

Take 1 hour before rolling with some grapefruit juice. The sugar will spike

your insulin and help the aminos cross the blood brain barrier. You will be

amazed.

1-3 are amino acids, precursors of serotonin, dopamine & noradrenaline. 4 is

another amino acid - it's like glucose for the brain.

5 is required for neurotransmitter production and is a good antioxidant.

5-HTP is the most important supplement so don't be tempted to skip it. If

you don't want to neck all that lot then skip the Tyrosine & DLPA, although

they do have a noticeable effect in most people. I would take it about an

hour ahead of time and the juice does make a difference.

The basic idea is that MDMA will deplete stores of the neurotransmitters in

your brain. The MDMA experience is largely caused by your neurons firing

rapidly and releasing Serotonin & Dopamine. Supplementing your diet with the

precursors to these neurotransmitters will ensure that you get the maximum

out of the MDMA. The supplements are not drugs themselves, they are

nutrients.

Serotonin = empathy, contentment, bliss, love, head rushes

Dopamine = energy, euphoria, body rushes ((the 'speedy' effect)

5-HTP replaces Serotonin. Tyrosine & DLPA replace Dopamine. DLPA also has

other functions but I'm not clear on them and they're not too important in

this context. These aminos will circulate in the bloodstream and some will

cross the Blood-Brain Barrier and be synthesised into the appropriate

neurotransmitter.

Take one hour before dropping your pill. Any fruit juice will do by the way.

I usually take Cola anyway for the additional caffeine. You should not eat

for 3-4 hours before you drop. If you get hungry eat foods containing no

protein as proteins will break down into amino acids and reduce the effect

of the pre-load. You should get a longer & stronger roll and not feel so

fucked afterwards.

Additional information contributed by Kallisti -Malaclypse the Youngst KSC

(Mal-3) :

Magnesium cuts down on jaw clenching. B6 is required for the conversion of

5-HTP into 5HT so taking some Vitamin B6 might help. 5-HTP should be taken

after, maybe with an SSRI (prozac, Zolaf, etc) to cut down on the axon

trimming and serotonin depletion that occurs afterwards and creates

tolerance and "Post-E Depression".

[e-tarded]

Dr. Tom who wrote that article , is an actual doctor

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~*P*L*U*R*~

Four Simple Words To Live By....

[blackjack]

Dr. Jack,

It was from a magazine....My friend emailed it to me today, Ill try to get the name of the author for you tomorrow...

Dr. Tom

[blackjack]

But any initial reactions to that article? I know you are pretty knowledgeable about the subject and really research your stuff...Just off the top of your head any initial reactions PROs/CONs to the article?

BlackJack

[sonicgroov]

interesting...interesting about the dopamine precursors...will that help to make a speedy roll. im gonna try all that.

peace out

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~~ TrYpDaLyTeFaNtAsTiC ~~

I scream I scream so much you know what I mean, this electric stream, my tears in league with wires and energy, my machine this is my beautiful dream dream dream, Of hurting no one, hurting no one, hurting no one, I'm hurting no one I wanna give you everything I wanna give you energy, I wanna give a good thing I wanna give you everything

-underworld

[millele]

sounds like a lot of prep time and work. my friends and i will take 5-htp after rolling to counteract the e-pression effects, and while rolling, we'll sometimes take a vitamin c pill to prolong the roll. also, if we plan on rolling 2 nights in a row, definitely take 5-htp after the first night and periodically the next day before rolling again, to build up your seratonin.

in my opinion, i don't know how much the vitamin c really works in prolonging your roll, but the 5-htp is a must. it is expensive though, something like $10-$12/bottle!

[kramadas]

Wow...actually I have all the stuff, but never took anything but the 5-HTP and Vit C. And Millie, the 5-Htp is more like $20/bottle.

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"I would believe only in a god who could dance."

Nietzche

[e-tarded]

I don't remember where I read it, but I have heard taking tyrosine isn't such a good idea. The guy who wrote that on the mdma clearing house is Dr. Tom. He is a licensed doctor down south. He actually still visits www.bluelight.nu and the Hive.

------------------

~*P*L*U*R*~

Four Simple Words To Live By....

[blackjack]

I have taken the 5HTP, VIT C, and VIT B6 but none of the others....I read that a while back there was a bad batch of tyrosine that was going around, so it really got a bad rep. Not sure about it at all, so ill have to look into it, but the quantities do seem to be quite large (500-1000mg), heck even with the 5HTP, to take up to 500 mg at one time will definately make your stomach very quizzy. I take about 200-300 mg spread out over a two hour period prior to taking the tab. And I never feel any stomach discomfort from that. But more importantly is to take 200mg or so when/and after you are coming down (Especially if you suffer from E-Depression). As for the other components I have never tried them, hell I dont even know what DLPA is? Can anyone expand on this vitamin?

Blackjack