Only you can tell yourself what to do, you will know when enoughs-enough, and you can't handle the pain and aggravtion anymore. I went through this same exact thing, right down to the vacation, and fighting w/ her while we were in Europe. We fought for 2 weeks off and one, then the day after we got home from Europe, we broke up and haven't talked since, and it was the best decision I have ever made... I just knew that I had had enuff of the fighting and pain..