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Cutoff and Detection Post Dose

The immunoassay technique used to detect PCP in urine has a cutoff level of 25 ng/ml. PCP is cleared from the bloodstream with a relatively long half life of 7-11 hours. Because it is a lipid (fat) soluble drug, detection in the urine is possible up to 48 hours or longer post dose. Blood levels correspond much better than urine to behavioral effects, i.e. being under the influence, but urine is a better screening fluid since drugs are concentrated for elimination. Confirmation levels on GC/MS is 25 ng/ml.

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