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elitesnautica

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  1. elitesnautica

    Playboy!?

    Depends on which playmate, I was poseing with. nautica
  2. ALA Is an anti-oxidant that is both fat and water soluble. Most anitoxidants are either fat or water soluble not both. For example, Vit C is water soluble where as Vit E is fat soluble. With this being said - ALA is the greatest anit-oxidant know to man and should be taken by every one if possible. Recommended dosage is anywhere from 200-600 mgs per day. Personally, I take up to 3000 mg per day. At this dosage I seem to notice that my insulin spike is less and it also does seem to be mildly anabolic. Side effects. 1) heart burn - must drink plenty of water to get it down. 2) At the higher dosage - I would get tired for an hour or so. Also, you do not neccessarily need the R-ala, the other seems to work fine you just need a little more of it. Cheapest place to order on the net. www.anabolical.com - the owner of this site is a good guy and provides good service. (I have not needed to buy any in a couple of months but I am sure he is still doing business.) Nautica
  3. I am not sure how many carbs are in this product. Personally, when I look for protein drinks - I look for drinks low in carbs and fat and NO sugar if possible. I get plenty of carbs and fat from other sources. Also, 78 grams per serving is alot of protein. I do not see your body being able to process this much protein at one sitting without the increased protein synthesis caused by AAS. Nautica
  4. Thanks for the vote of confidence shroomy. Nautica
  5. Also, why not post a pic - that will give us more to go on. Nautica
  6. Good info above. As far as supplements go. Stick with the basics. PROTEIN, ALA, GLUTAMINE AND CREATINE. Do not buy PROHORMONES. They are harder on the system than juice They are more expensive than juice They do not work nearly as well as juice and most do not work at all. also, while bulking do not worry about fat. EAT, EAT AND EAT SOME MORE. Get in your basic 200-300 grams of protein, 500 grams of good carbs and than anything else you can put down. This spring you can concentrate on the fat. Bulking is not a science like cutting is. There is no formula other than to eat. Good luck Nautica
  7. you can delete it yourself - go down to the edit/delete button. nautica
  8. its winter - your suppose to be fat. Just get in shape before summer time. Nothing worse than a fat girl in a bikini, except for maybe a fat guy in a speedo. Nautica
  9. why would I want to hit it. I couldn't do it any good if i did. nautica
  10. Creatine will be absorbed better with anything that creates an insulin spike. I have also read some reports that grapefruit juice helps it as well. nautica
  11. Any product you buy will be no better than water. If you fear you have metabolites in your system when you take the test then just dilute your urine with water. Don't waste your money on flushing products. The few that do work are tested for and will show up on a drug test. Nautica
  12. If you are not going to take drugs between now and then you have nothing to worry about. Just exercise and eat - that will help metabolise any drugs still in your system. nautica
  13. Yes, just about any oral medication that is absorbed through the gut or intenstins will be effected. Also, the drugs metabolised through the liver will not be directly effected but will have less degredation in the gut; allowing more to be available in the liver. nautica
  14. How Grapefruit juice works Written by LewdTenant of AR. When we take a medicine orally (by mouth), it has to get into our blood stream to do its job. (The medications that are intravenously administered, sidesteps this process and gets directly into the blood stream. That is why many of the medications that can be administered orally and intravenously, can be safely used in the intravenous route, while the oral route are subject to interactions.) The absorption usually takes place in the large or small intestines. The liver plays a key role in many of these metabolism b y removing a significant amount of the medication from the serum. For many medications, there is an optimum concentration of the active ingredient that need to be present in the serum for a certain amount of time for it to work. So, two factors are important. The maximum concentration of the active ingredient in the serum (called Cmax). The time factor is determined by plotting the concentration in the blood stream versus time and determining the area under the curve (AUC). Obviously, more AUC means we had been exposed to this ingredient for a longer time. Any mechanism that alters the optimum values of Cmax and AUC can affect the way the drug reacts. We will see later that grapefruit affects both Cmac and AUC for several prescription medications that take advantage of the Cytochrome P450 isoenzyme for the metabolism of the drug. All drugs and many other substances within our body such as prostaglandins, fatty acids and steroids, utilize one or more of the cytochrome P450 isoenzymes in their respective metabolic (elimination) pathways. It turns out that one of the most important dietary factors that affects this isoenzyme is a bioflavinoid and possibly other ingredients contained in grapefruits and in grapefruit juice. INTERACTIONS OF GRAPEFRUIT WITH MEDICATIONS Grapefruit juice affects the bioavailability (therapeutic concentration) of a very wide variety of drugs. All drugs, to greatly differing degrees, achieve their respective target therapeutic levels by two main regulatory pathways, both involving one or more of the 30+ related cytochrome P450 isozymes. The initial elimination route, called the presystemic "first-pass" metabolic pathway, involves the the gut (small intestine), the portal vein and the the liver. Depending on the drug or food supplement in question, this critical "first-pass" metabolic degradation will directly determine both the peak and mean concentrations of the drug or its metabolite in the blood stream. Some drugs, such as terfenadine (Seldane) requires 100% breakdown by this presystemic "first-pass" metabolic pathway to convert it to its active and less toxic metabolite, terfenadine carboxylate. Any drug, (such as erythromycin, ketoconazole (Nizoral)) or food such as grapefruit juice, that inhibits or competes for the enteric (gut) cytochrome P-450 3A4 isozyme, will partially or completely block this metabolic step (breakdown) of terfenadine, and will result in the absorption of unmetabolized terfenadine, with the potential for very serious toxic reactions including ventricular tachyarrithmias (cardiac arrest) and death. Approximately one hundred and twenty five deaths have now been linked to the concomitant use of terfenadine and one of the previously listed products that interferes with the Cytochrome P450 isoenzyme. Other drugs, e.g. prednisone, quinidine, theophylline, etc. with a high oral bioavailibility, or not competing for the same cytochrome P-450 3A4 isozyme, will not be affected by ingestion with grapefruit juice. The second elimination pathway for all drugs involves the more predictable metabolic degradation over time by the hepatocytes in the liver, and excretion in the bile or by the kidneys. Grapefruit juice will not have any effect on the drugs that uses this second elimination pathway. It only affect the "first-pass" small intestine - liver metabolic pathway and not any secondary elimination metabolic processes. That is why some drugs are affected by grapefruit juice while others are not. INTERACTIONS OF GRAPEFRUIT WITH MEDICATIONS Dr. David Bailey and Associates at the University of Western Ontario, Canada showed that grapefruit juice acts by blocking (down regulating) the activity (expression) of cytochrome P450 3A4 isoenzyme in the intestinal wall, thereby preventing the presystemic "first-pass" oxidative metabolism (breakdown) for a wide variety of drugs. Grapefruit juice did not significantly block cytochrome P-450 3A4 isozymes in the liver hepatocytes. The net result of blocking this presystemic "first-pass" metabolic pathway, is the potential for a marked increase in the plasma concentration of the drug, often to the point of toxicity. For example, in the case of a drug called felodipine (Renedil & Plendil) which they were investigating at the time, there was more than a five fold increase in the plasma concentration with grapefruit juice as compared with water. Other studies with the cholesterol lowering drug, lovastatin (Mevacor), showed that grapefruit juice was capable of increasing the peak serum concentration of this drug up to 19.7-fold (range 5.2-19.7) and the area under the concentration-time curve (AUC) up to 26.3-fold (range 5.7-26.3). The magnitude of the interaction with grapefruit juice appears to be highly variable among individuals, but the effect is relatively consistent for any given person. In addition, there appears to be considerable interracial genetic polymorphism of the cytochrome P450 isozyme subtypes. The cytochrome P450 isoenzyme suppression activity of grapefruit juice was found to be accumulative, with an estimated half life at around 12 hours. The suppression effect at the enteric (gut) level, appears to be caused by a degrading (destruction) and not only suppression of the Cytochrome P450 3A4 isozyme. The return of cytochrome P450 3A4 isoenzyme activity appears to require de novo cytochrome P450 isozyme synthesis, further prolonging the effects of grapefruit juice. Further studies have shown that grapefruit juice will also block other Cytochrome P450 isoenzymes, viz. 1A2 & 3A3. The magnitude of the effects from inhibition of cytochrome P450 1A2 & 3A3 isoenzyme activity by grapefruit juice is relatively minor in comparison to its 3A4 activity, and the clinical significance is relatively unknown. INTERACTIONS OF GRAPEFRUIT WITH MEDICATIONS The potential for this type of drug interaction is enormous. Dr. David Bailey, stated in the September 3rd, 1998 issue of the Medical Tribune: "Sixty percent of drugs that are (commonly) prescribed are metabolized to some extent by this enzyme, CYP3A4 (Cytochrome P450 3A4). Many drugs undergo first-pass metabolism by CYP3A4. Hence, the inhibition of this enzyme in the gut causes plasma concentrations of these drugs to increase markedly after oral administration. The result can be significant. For example, taking one tablet of lovastatin (Mevacor) with a glass of grapefruit juice is the same as taking 12 to 15 tablets with a glass of water. Certain antihistamines, benzodiazepines, cyclosporin, caffeine, calcium antagonists and cisapride are among other drugs with which grapefruit interacts. So this interaction is very important and the list (of drugs) is going to continue to grow". The list of specific drugs and drug types which interact with grapefruit juice is slowly expanding, but still very incomplete. We will take a look at few of these where clinical data is available. Summary: Medications That are Affected by Grapefruit Juice Use these are all substrates of Cytochrome P450 Statins (Cholesterol Lowering Drugs): -Baycol (Cerivastatin) -Mevacor (Lovastatin) -Lipitor (Atorvastatin) -Zocor (Simvastatin) Antihistamines: -Ebastine -Seldane (Terfenadine, taken off the U.S. market) Calcium Channel Blockers (Blood Pressure Drugs): -Nimotop (Nimodipine) -Nitrendipine -Plendil (Felodipine) -Pranidipine -Sular (Nisoldipine) Psychiatric Medications: -Buspar (Buspirone) -Halcion (Triazolam) -Tegretol (Carbamazepine) -Valium (Diazepam) -Versed (Midazolam) Intestinal Medications: -Propulsid (Cisapride, taken off the U.S. market) Immune Suppressants: -Neoral (Cyclosporine) -Prograf (Tacrolimus) Pain Medications: -Methadone Impotence Drug: -Viagra (Sildenafil) Miscellaneous -Losartan (for lowering blood pressure) - Grapefruit juice inhibits the body's ability to absorb the drug. -Digoxin (for treating congestive heart failure) - Grapefruit juice inhibits the body's ability to absorb the drug. INTERACTIONS OF GRAPEFRUIT WITH MEDICATIONS Foods That Affect Cytochrome P450 The following foods are known to interact with cytochrome P450 isoenzyme. If you are taking any medication that utilizes P450 for its metabolism, you may want to avoide the following foods: Inducers Broccoli Fried and charcoal broiled foods Insulin tobacco ethanol St John's Wort HIV anti-virals barbituates prednisone(corticosteroid) Inhibitors ketoconazole(Nizoral) cocaine Grapefruit I believe the ones below are all inducers but did not have time to verify Cabbage Other Cruciferous Vegetables Spinach Leeks Onion Garlic Parsley Smoked fish or meat Ham Sausage Conclusion Grapefruit's effect on medications is unpredictable. It may enhance the desired effect of the drug in some instances (so that we can take a lower amount of the drug and still get the effectiveness). It also means that if you take the suggested dose of the drug, our system gets a higher than expected concentration of the drug, resulting in amplification of the side effects of the drug and sometimes resulting in dangerous situations that was unforeseen at the time of the introduction of the drug in question. The same dose of drug could produce blood levels in different individuals ranging in concentration from normal to very toxic. Depending on the individual and the drug in question, dangerously high levels of the drug could enter the systemic circulation.
  15. Nice - transdermal speed. i like how they do not list the herbs that are included. Maybe that is b/c you can buy them at speedy mart for $3. Nautica
  16. i haven't made very many women squirt, but I have squirted on a few women. Nautica
  17. I think I will stay in Arkansas. I br apt - $350.000 New 1600 SqFT. house - $100,000.00 View of the Arkansas River Valley - Priceless. nautica
  18. Not sure what extracirriculars are. But, cialis is great. It takes a little while to start working but after it kicks in it is unbelievable. But I guess everyone reacts different. Nautica
  19. It is a 36 hour pill that has not hit the market as of yet. Some people have stole the patent and are manufacturing it now. It is a replacement for viagra. You dont get the side effects that you do with viagra and it works 3 to 4 times as long. Increases blood flow and sensitivity to the genetials for both males and females. Good shit. It cost around $3 per pill on the black market and it is well worth the money. (Even if you do not have erection problems it is worth it.) http://boards.elitefitness.com/foru...ighlight=cialis Nautica
  20. If you only knew - cialis kicks ass. Nautica
  21. It is a 36 hour pill that has not hit the market as of yet. Some people have stole the patent and are manufacturing it now. It is a replacement for viagra. You dont get the side effects that you do with viagra and it works 3 to 4 times as long. Increases blood flow and sensitivity to the genetials for both males and females. Good shit. It cost around $3 per pill on the black market and it is well worth the money. (Even if you do not have erection problems it is worth it.) http://boards.elitefitness.com/forum/showthread.php?s=&threadid=147802&highlight=cialis Nautica btw - tony shoot me an email - I lost yours. nautica@elitefitness.com
  22. It didn't hurt any that my girl and I had both taken a cialis before we went dancing. Nautica
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