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nifer

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Everything posted by nifer

  1. I can't really see these being legalized unless there is a complete goverment overhaul - and we know that wont happen anytime soon. I think decriminalization is more feasible
  2. http://www.mygem.net/keving/wmc.htm
  3. nifer

    hair gel

    Redken water wax (not as sticky as gel) - takes care of flyaways and lightly "molds" hair Tigi enviro spray - mist lightly and it'll hold your style lightly while combatting humidity
  4. Fluid (4 and south) on Fridays (Rich Medina & Dennis Perez - house - tribal, afro) and Saturdays (Sean Thomas & Pete Oss - deep house) are good. Soma (3 btwn Chestnut and market) on Fridays has Lorne and Saturdays its Cozmic Cat. Lucy's (3 and market) has Ricky Lee on Fridays and Benja Coleman on Saturdays. Soma and Lucy's have no cover but are 21+. If you're under 21, Motion has Angel Alanis and Eric Davenport on Friday. Every sunday at Lucy's has Drunken Monkey. You pay 20$ for free food, unlimited mimosas, bloody marys and drafts from 12-8pm. Roland Riso spins nu jazz, funk, deep house and classics. Most places don't have a strict dress code. Just look somewhat fashionable and don't wear sneakers or a baseball cap. As for shopping - Liberty One (16-17 and chestnut) has jcrew, victorias secret, ann taylor, aldo, godiva, aveda, and other stores. There are also a bunch of stores on Walnut St. btwn Broad st. and Rittenhouse Square (kenneth cole, bebe, origins, urban outfitters, anthropologie, banana republic, ralph lauren).
  5. Source: American Chemical Society (http://www.acs.org/) Date: Posted 8/16/2001 Ecstasy Component May Help Researchers Measure Brain Damage From The Drug Researchers in Spain have isolated for the first time a by-product of the illicit drug Ecstasy that is believed to cause some of the brain damage associated with the drug. They believe their finding will help them measure, with greater precision, the long-term neurotoxicity of Ecstasy in human users. The report will be published in the September issue of Chemical Research in Toxicology, a peer-reviewed journal of the American Chemical Society, the world’s largest scientific society. The findings may corroborate speculation that HHMA (3,4 dihydroxymethamphetamine), is at least partially responsible for Ecstasy’s harm to the human brain, according to lead researcher Rafael de la Torre, D.Pharm., of the Municipal Institute of Medical Research in Barcelona. Previous study had linked HHMA to many of Ecstasy’s known side effects, but until now researchers had not been able to accurately measure the amounts of HHMA in users. HHMA is created when Ecstasy (known chemically as MDMA, or 3,4- methylenedioxymethamphetamine) is metabolized through the liver. Animal studies have shown Ecstasy to damage the brain’s thought and memory function, but research has indicated that such side effects don’t develop until the drug is metabolized. Accurately measuring the amount and concentration of HHMA in a person’s body can provide new insight into the drug’s effects, including how it is metabolized, and possibly determine its long-term effects, de la Torre said. HHMA does not occur naturally in the body and thus would not be found in a non-user of Ecstasy, he noted. “This observation concerns not only Ecstasy’s acute effects, but more interestingly, its mid- and long-term neurotoxicity,” de la Torre said. “The detection of HHMA was hampered up to now by problems measuring it in humans, which we have solved.” The research represents the first validated method for measuring HHMA in body fluids, according to de la Torre. It involved four men who each volunteered to take a 100-milligram dose of Ecstasy and submit blood and urine samples regularly for the following 24 hours. All were described as regular users of the drug. The researchers found nearly identical concentrations of HHMA and MDMA in the samples, establishing HHMA as a likely contributor to conditions associated with Ecstasy use, de la Torre said. In widespread use since the 1980s, Ecstasy is a stimulant with effects similar to the short-term euphoria and increased alertness claimed by cocaine users, according to the National Institute on Drug Abuse. It is considered dangerous, however, since it has been shown to damage nerve cells in the brain critical for thought and memory, NIDA reports. Other experiments show that people who take MDMA score lower on memory tests and that animals have persistent effects from the drug six to seven years after exposure.
  6. it depends on what terms you guys broke up. she could be ready to be your friend again - and nothing more. i have recently "re-friended" (if there is such a word) an ex of mine. we were together for two years. now we are almost like best buddies - asking each other for advice and input on our own seperate relationships. actually i have become friends again with most of my ex's. if having a plutonic relationship w/ an ex bothers you, then you obviously still have unresolved issues with that person. personally, i wouldn't waste energy on harboring negative thoughts about a relationship that doesn't even exsist anymore. just my two cents
  7. ok ok ok. i remember it was hard as hell trying to find test subjects to participate in my senior thesis experiment a)I live for the moment 3 b)Developments in the media have influenced club culture 3 c)All clubs are the same 1 d)Superclubs (Cream, Ministry of Sound, Gatecrasher) have lost touch with reality 4 e)The music within club culture has the smae impact on me as it always has 4 f)Accurate information on club culture is readily available 2 g)I do not take life seriously 1 h)Club culture will last another 13 years 5 i)Club culture is experienced equally by men and women 5 j)Club culture is heterosexual 1 k)A persons ethnic origin will determine a positive experience of club culture 2 l)Club culture is not politically orientated 4 m)A person from the working class may not enjoy their experience of club culture in the same way as someone from the middle class 2 n)An individuals religion will distance them from club culture 2 o)Club culture is distanced from reality 2 p)Ecstasy enbles an escape from reality 4 q)There is on theory to explain all social life 1 r)The media present a distorted image of club culture 4 s)Club culture can be split into many different musical genres, but no one is dominant 2 t)There are no social constraints in club culture 2 u)Variety will be an important factor in the continuation of club culture 4 v)Club culture cannot keep reinventing itself 3 good luck
  8. nifer

    I'm in HELL

    shitty i hope you kicked her ass to the curb
  9. thanks for your help
  10. ehmm... youre serious? you may only have created one child you know of. and there is such a thing called abortion. anyways... even with *one* kid, sounds as if maybe you arent even ready to handle him/her.
  11. I was searching on the net for cheapish prices on cartridges. i found one site, www.123dj.com, that seems to have very good deals. im skeptical about buying anything from there though, since noone i have spoken with has ever heard of them before. does anyone know anything about this site? or can anyone direct me to any other places that have competitive prices?
  12. what were the rates they were quoted?
  13. blue six "lets do it together" naked music
  14. trash... excessive trash... polluting the environment. this *is* an outdoor party.
  15. from the man Hito himself.... party people in the place to be...Feb. @ Fluid is going to be slammin!! Check it out: Special Guest DJ spots for Feb: Wed. 2/6: ?uestlove + Jazzy Jeff spinning HOUSE!!(Unlimited) Thurs. 2/7: Shimon + Red One from the UK(Platinum) Fri. 2/8: Vikter Duplaix w/ Rich Medina + Dennis Perez(Afrorikan Vybe) Wed. 2/13: Lee Burridge(UK) w/ Vincent Wonder + Summerjoy(Unlimited) Fluid Night Club 613 S. 4th St.(above The Latest Dish) 215.629.3686 www.Fluidnightclub.com ____________________________________________________ and from Imri... Saturdays in Philadelphia are about to get exciting again. Starting February 9 2002, the DJs take control. Every week we will be showcasing your favorite established local talent, along with the true motion residents DJs on the main floor. Up in the skydome, Philly's top turntablists. No dress code. No cheese.... > L O C A L > M O T I O N 02.09.02 > OPENING NIGHT house > breaks > trance hypersonic tag team action IMRI X ANDEE JEFF HEART X MINDBENDER MASS X CARL MICHAELS JONATHAN WILLIAMS X WONDER plus hip-hop in the skydome RICKY LEE X KWESTION Motion: 953 North Front Street Philadelphia PA USA Earth Doors open 9pm-2am. 17+ to enter. Please bring your ID. for more info, visit our site: http:://www.motionevents.com LOCAL>MOTION: Every Saturday night!!! only $5. more bang for your buck. check out the flyer here: http://reflective.net/localmotion
  16. you had to be "picked" to get into vinyl? ive gone there many a time and have seen people dressed in jeans and sneakers *shrug*
  17. NATIONAL INSTITUTES OF HEALTH National Institute on Drug Abuse Bethesda, Maryland, June 27, 1997 Long-term use of marijuana produces changes in the brain that are similar to those seen after long-term use of other major drugs of abuse such as cocaine, heroin, and alcohol. Moreover, these changes may increase a user's vulnerability to addiction to other abusable drugs by "priming" the brain to be more easily changed by drugs in the future. This study is published in the June 27 issue of Science. "We know that a substantial number of chronic marijuana users become addicted, and previous research with animals has shown that stopping heavy marijuana use suddenly can cause distinct withdrawal symptoms," said Dr. Alan I. Leshner, director of the National Institute on Drug Abuse, National Institutes of Health, which supported this research. "This study shows that marijuana use shares common brain changes and mechanisms with other drugs of abuse." This study was conducted by scientists in the United States and Spain to discover whether CRF (corticotropin- releasing factor), a brain chemical which increases during emotional times and periods of stress, plays a role in dependence on cannabis, the plant from which marijuana and hashish are derived. Earlier studies have suggested that CRF plays a role in the neurobiological and behavioral effects of withdrawal from addiction to cocaine, alcohol, and opiates, and possibly a role in drug dependence in general. Rats were injected with HU-210, a potent substance that mimics the effects of marijuana. An analysis of the rats' brains showed that one injection of HU-210 reduced the release of CRF in the amygdala, a key brain structure involved in emotions. After 14 days of HU-210 treatment, the researchers induced drug withdrawal by injecting rats with the antagonist SR 141716A, a substance that blocks many effects of marijuana. The marijuana-treated rats showed many withdrawal symptoms after marijuana antagonist injection. Moreover, these rats showed an increased release of CRF at the same time they demonstrated dramatic behavioral withdrawal symptoms. Importantly, the specific brain areas that were activated during cannabinoid withdrawal are quite active during withdrawal from other drugs of abuse and play a key role in stress responses in general. "These results provide evidence that long-term exposure to cannabinoids leads to changes in the brain that activate stress-like responses during cannabinoid withdrawal," said Dr. Friedbert Weiss, one of the study's investigators at the Scripps Research Institute in La Jolla, CA. "These changes in CRF functioning in the brain are similar to those seen during withdrawal from alcohol, cocaine, and opiates, as well as during exposure to environmental stressors," he added. Dr. George Koob, also from Scripps Research Institute, observed that "the finding from this and other studies that long-term exposure to cannabinoids can produce changes in the brain that resemble those associated with other major drugs of abuse suggests that addiction to one drug may make a person more vulnerable to abuse and addiction to other drugs. Cannabinoid abuse, by activating CRF mechanisms, may lead to a subtle disruption of brain processes that are then 'primed' for further and easier disruption by other drugs of abuse." The study was supported in the United States by the National Institute on Drug Abuse and the National Institute of Diabetes, Digestive and Kidney Diseases, both parts of the National Institutes of Health, and in Spain, by the Comision Interministerial de Ciencia y Tecnologia, and Comunidad Autonoma de Madrid.
  18. "are you sleeping" by indo on azuli records
  19. mj cole artful dodger dreem team footloose (yes he plays d&b also) dem 2 tuff jam wookie so solid precursors: "never let you go" tina moore "my desire" amira go to www.ukflex.com
  20. i doubt that using one of these "miracle" ab contraptions works if thats the only work out youre getting. if someone doesnt bother to take care of themselves by eating well and exercisng a little they cant expect a great bod well...unless you go for plastic surgery *ick*
  21. Cup size? puahahaha what are the dick sizes on you guys?
  22. ewww.. neither. if youre a guy, go with Lab Series for men, or even Clinique for men grrls go with Lancome or Shiseido
  23. Amphetamines cause CNS stimulation that may induce euphoria; intensify emotions; alter self-esteem; and increase alertness, aggression, and sexual appetite. In the brain, presynaptic reuptake of catecholamines (ie, dopamine, norepinephrine) is blocked, causing hyperstimulation at selected postsynaptic neuron receptors. Indirect sympathomimetic effects of amphetamines also are caused by blocking presynaptic vesicular storage and by reducing cytoplastic destruction of catecholamines by inhibiting mitochondrial monoamine oxidase. Indirectly, these hyperstimulated neurons can stimulate various other noncatecholaminergic central and peripheral nervous pathways. Sympathomimetic stimulation of central and peripheral pathways by most amphetamines may occur directly but to a much lesser extent than with ephedrine. Changes in mood, excitation, motor movements, sensory perception, and appetite appear to be mediated more directly by central dopaminergic alterations. It has been postulated that serotonin alterations contribute to the amphetamine-related mood changes, psychotic behavior, and aggressiveness. In humans, the half-life of methamphetamine ranges from 10-20 hours, depending on the urine pH (half-life is shorter in acidic urine), history of recent use, and dosage. Methamphetamine has greater CNS effects compared to D-amphetamine, presumably because of the prolonged half-life and increased CNS penetration. A portion of methamphetamine is metabolized to amphetamine. Methamphetamine is absorbed readily from the gut, airway, nasopharynx, muscle, placenta, and vagina. Peak plasma levels are observed approximately 30 minutes after IV or IM routes and 2-3 hours postingestion. Rapid tissue redistribution occurs with steady-state cerebrospinal fluid levels of about 80% of plasma levels. Hepatic conjugation pathways with glucuronide and glycine additions can result in inactivation and urine excretion of amphetamine metabolites. When methamphetamine is used with ethanol, increased psychological and cardiac effects are observed. This is presumed to be the result of pharmacodynamic rather than pharmacokinetic interactions. Similarly, the increased toxicity of simultaneously used opioids and amphetamines, such as methamphetamine (ie, speedballing), appear to result from pharmacodynamic interactions. The euphoric effects produced by methamphetamine, cocaine, and various designer amphetamines are similar and may be difficult to clinically differentiate. A distinguishing clinical feature is the longer pharmacokinetic and pharmacodynamic half-life of methamphetamine, which may be as much as 10 times longer than the half-life of cocaine. Animal studies with D-amphetamine and cocaine suggest that some differences in underlying mechanisms of toxicity may exist between these agents. Because of the variability in quality and concentration of illicitly purchased methamphetamines, the clinical observation of toxic effects usually is more relevant than an estimate of total ingested dose. Although hair and saliva analysis have been reported, most toxicological monitoring or testing is performed with urine and blood samples.
  24. nifer

    E vs K

    from nih.gov MDMA (Ecstasy) MDMA is a synthetic, psychoactive drug with both stimulant (amphetamine-like) and hallucinogenic (LSD-like) properties. Street names for MDMA include Ecstasy, Adam, XTC, hug, beans, and love drug. Its chemical structure (3-4 methylenedioxymethamphetamine, "MDMA") is similar to methamphetamine, methylenedioxyamphetamine (MDA), and mescaline - these are synthetic drugs known to cause brain damage. MDMA usually is taken in pill form, but some users snort it, inject it, or use it in suppository form. Many problems MDMA users encounter are similar to those found with the use of amphetamines and cocaine. Psychological difficulties can include confusion, depression, sleep problems, severe anxiety, and paranoia. Physical problems can include muscle tension, involuntary teeth clenching, nausea, blurred vision, faintness, and chills or sweating. Use of the drug has also been associated with increases in heart rate and blood pressure, which are special risks for people with circulatory or heart disease. Recent research also links MDMA use to long-term damage to those parts of the brain critical to thought, memory, and pleasure. MDMA use is increasing in most metropolitan areas of the United States.* In Boston and New York City, it appears to be spreading beyond the club scene to the streets. Content of the MDMA pills also varies widely, and may include caffeine, dextromethorphan, heroin, and mescaline. In some areas of the country, the MDMA-like substance paramethoxyamphetamine (PMA) has been involved in the deaths of people who mistakenly thought they were taking true MDMA. The deaths were due to complications from hyperthermia. In a 5-year retrospective of emergency room mentions of club drugs,** the Substance Abuse and Mental Health Services Administration reports that emergency room mentions involving MDMA increased from 250 in 1994 to 2,850 in 1999. Ketamine Ketamine is an anesthetic that has been approved for both human and animal use in medical settings since 1970; about 90 percent of the ketamine legally sold is intended for veterinary use. It can be injected or snorted. Ketamine is also known as "Special K" or "vitamin K". Certain doses of ketamine can cause dream-like states and hallucinations, and it has become common in club and rave scenes and has been used as a date rape drug. At high doses, ketamine can cause delirium, amnesia, impaired motor function, high blood pressure, depression, and potentially fatal respiratory problems. Emergency room mentions of ketamine rose from 19 in 1994 to 396 in 1999.** Recent use has been reported more frequently among white youth in many cities, including Atlanta, Baltimore, Boston, Chicago, Minneapolis/St. Paul, Newark, New York City, Phoenix, San Diego, Texas, and Washington, DC.*
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