e-tarded

try www.pillreports.com ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Neurotoxicity For an explicit definition of neurotixicity and its legal implications, refer to the site listed below. http://www.epa.gov/ncea/pdfs/nurotox.pdf To begin, animal studies show that, the list below, accurately defines the process in which neurotoxicity is allowed to manifest into a serious problem. (Credit to Deep) 1) MDMA amps up seratonin and dopamine levels 2) Seratonin runs out 3) Dopamine goes where seratonin normally would 4)Altered dopamine molocules cause damage to nerves. To begin, MAPS has done extensive research in the affects of neurotoxicity and their argument stands up to studies performed and released by the Journal of Neuroscience. "MAPS" MDMA is no exception to the rule that every drug has serious side effects in some users. Reports indicate that a small number of the millions of people who have taken MDMA over the last several decades have suffered negative consequences. Some people may be predisposed to react unfavorably to typical amounts of MDMA while heavy users may be placing themselves at special risk. MDMA increases blood pressure, posing a risk to people with preexisting heart conditions. MDMA can also increase body temperature which, in combination with hot environments, exhausting physical exercise (prolonged dancing) and lack of fluids has been linked in very rare cases to death from heat exhaustion. MDMA's psychological effects have been occasionally associated with acute anxiety, panic and depression and are substantially context-dependent. Several cases of longer-lasting effects have been identified. While no causal link has been established connecting serotonin reductions to any negative consequences, the potential risks as well as the benefits of MDMA must be carefully weighed before any decisions can be made concerning appropriate uses. We owe our gratitude to Dr. Ricaurte and associates for conducting this latest study and to the National Institute on Drug Abuse (NIDA) for funding it. Now that this new study is completed, each of us entitled to make our own risk assessment after a careful look at the data. Below is my risk assessment, made with what I hope is a healthy dose of common sense. The Latest Scientific Study In August 1995, the Journal of Neuroscience published a scientific study by Fischer et al. investigating the regrowth of rat and primate brain neurons previously exposed to extremely large doses of MDMA. The study was designed to determine whether there was long-term restoration of normal levels of serotonin in those brain regions in which serotonin levels were previously reduced as a result of exposure to very large amounts of MDMA. Also examined was whether the regrowth of serotonin nerve terminals (reinnervation) restored the original brain structures. The study concluded that "in some rats and most monkeys, there is a lasting reorganization of ascending 5-HT [serotonin] axon projections following severe MDMA injury. In particular, while some projections (e.g. those to the neocortex) fail to recover for up to 18 months after drug administration, others (e.g. projections to the basal forebrain) recover fully, sometimes in excess." The authors of the paper noted that the "aberrant serotonergic brain reinnervation" had no known functional consequences, but that "if 5-HT [serotonin] function declines with age, MDMA-exposed individuals could be at increased risk for developing age-related cognitive impairment."(2) The Media Coverage The results of the study were reported in newspapers all across the United States and Europe. The reports began with an article in the August 15, 1995 New York Times Science Section incorrectly stating that the animals were given "recreational doses of MDMA - the amounts taken by many young people." In terms of human use, Dr. Ricaurte was cited as stating that "people could probably take normal amounts of MDMA three or four times a year without noticing any neuropsychiatric problems but people who took seven or eight doses a night could be inviting problems." Published at the same time, but with a decidedly more alarming spin, was a report by the Associated Press (AP) wire service in which Dr. Ricaurte was quoted (he feels misquoted) as stating simplistically that "Results suggest that people who have used (Ecstasy) in the past have some kind of (brain) damage." To emphasize the point, the article quoted Dr. Robert Daroff, chief of staff at University Hospitals in Cleveland and editor-in-chief of the journal Neurology, as saying that "It makes you feel good, but you are going to probably get hurt." The only counterpoint to these reports that I'm aware of was a letter to the editor that I co-wrote with Neal Goldsmith, Ph.D., published in the August 24, 1995 New York Times. We pointed out that the doses used in Dr. Ricaurte's study were roughly 45 times larger than the typical human dose, and that MDMA had been used "in therapeutic, sacramental and recreational contexts for over 20 years by hundreds of thousands of people without evidence of harmful neurotoxic effects on appetite, sleep, mood, impulsiveness or other neurological functions." On August 31, 1995 another story about the study was published in the British New Scientist magazine, and the London branch of the Reuters News Service distributed a story that was widely disseminated on the Internet. In both these stories, Dr. Ricaurte was quoted as stating, "If there is a margin of safety, it is not a large margin." On September 2, 1995, yet another letter to the editor was published in the New York Times, this one by Richard A. Friedman, MD, Assistant Professor of Psychiatry, NY Hospital-Cornell Medical Center. He accused Dr. Goldsmith and me of entertaining ideas that were "dangerously naive and without scientific merit." He went on to assert that reports that MDMA had therapeutic benefits were pure speculation because "there are no long-term scientific studies of the effects of MDMA in humans," and that "lack of evidence of MDMA's possible dangers is by no means proof of its safety." Of course, Dr. Friedman was correct to assert that MDMA has not been proven safe; such a proposition can never be proven, only disproven. Furthermore, Dr. Friedman makes the valuable observation that drugs sold as MDMA "on the street" risk being contaminated. This risk of contamination complicates the question of "MDMA neurotoxicity." (The article then goes on to state more elaborately the arguments suggested, they came to this conclusion) Tentative Conclusion As with any substance, some people are likely to be particularly sensitive to relatively small amounts of MDMA. Other people take unusually large amounts, especially in recreational contexts. It would therefore not be surprising if some people took enough MDMA to cause long-term reductions in their levels of serotonin in some brain regions. What would be surprising is if these serotonin reductions are eventually shown to have significant harmful functional or behavioral effects. Such changes, if they do occur, could as easily be beneficial as harmful, especially considering the fact that many people report long-term benefits resulting from their use of MDMA. Over the last twenty years, millions of people have tried MDMA. This use of MDMA, though not conducted in the context of a scientifically controlled experiment, does provide an opportunity for a very large epidemiological study. Similarly, over fifty million people have tried a prescription drug called fenfluramine, a diet aid prescribed for daily use for months or years at a time that causes the same kind of neurotoxicity in animals as does MDMA.(9,10) The absence of a single confirmed case of functional or behavioral consequences related to serotonin neurotoxicity as a result of the use of fenfluramine(11) or MDMA does not mean that these drugs are without neurotoxic consequences. Appropriate epidemiological studies have not yet been conducted. Nevertheless, the lack of evidence of neurotoxic damage after such an enormous population of people has been exposed to these drugs certainly suggests that if any neurotoxicity-related problems have resulted, they are subtle and rare. It does seem possible that some physiological mechanism may partially explain the diminishing returns that many people report from continued use of MDMA. This is a negative consequence only to the extent that the MDMA experience is considered beneficial. After reviewing the new data reported by Fisher et al., I remain of the opinion that the risk of MDMA neurotoxicity is of no practical significance when typical or even somewhat larger doses of MDMA are used on an infrequent basis in therapeutic, sacramental or recreational contexts by people with normal brain function. Of course, I don't know this for sure, and neither does anyone else. I do know or have heard about many people who have used MDMA hundreds of times and seem unharmed and even helped by their use. As a result, I think that Dr. Ricaurte is being conservative when he states that "people could probably take normal amounts of MDMA three or four times a year without noticing any neuropsychiatric problems." While there is evidence that the neurotoxicity of MDMA can be blocked by the co-administration of Prozac or other selective-serotonin reuptake inhibitors (SSRIs) (12, 13) and that such drugs do not alter the MDMA experience in some people, (14) such protective measures do not seem to me to be necessary in normal use. Such measures might possibly be worth the trouble when exposure approaches seven or eight doses a night, a level which Dr. Ricaurte stated "could be inviting problems." Ironically, one could argue that MDMA neurotoxicity research in humans, with its spinal taps and injections of radioactive substances, is more dangerous than MDMA itself. Nevertheless, it is crucial that MDMA neurotoxicity research continue, and also research into the beneficial therapeutic uses of MDMA, so that the risks and benefits of MDMA can be accurately balanced. " -- Endnote Now, IMHO, the arguments on both sides were backed by personal beliefs. This is simply one report, I would not suggest using any less caution when using MDMA recreationally simply based on this knowledge. This is also an accurate depiction of how facts can be skewered and misinformation is doled out to the masses via media/news sources. The foremost thing to remember is that, while there has been no recognizable neurotoxic affects shown in this study, the pills that are sold in the street are most often not pure MDMA. A proper test will verify that your pills substance is pure. This article also states that Pre-Post loading is not necessary; However, the proper precursors to seratonin, namely 5HTP, in other studies, have proven quite affective as a deterrant. For a more in-depth look at this article, please visit the MAPS site below where this study was taken from. It further explains the arguments and conclusions listed above. http://www.maps.org/news-letters/v06n1/06108neu.html ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

try this site http://www.maps.org/news-letters/v07n3/07305tan.html ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Those sites are all well and good, but you might also want to check out some pharmacology sites. I have tons of research papers on E usage and Serotonin depletion from school. Let me know if you want them. Endorphins "Endorphins are a group of substances formed within the body that naturally relieve pain. They have a similar chemical structure to morphine. In addition to their analgesic affect, endorphins are thought to be involved in controlling the body's response to stress, regulating contractions of the intestinal wall, and determining mood. They may also regulate the release of hormones from the pituitary gland, notably growth hormone and the gonadotropin hormones." ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 10-09-2000).]

goto www.pillreports.com ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

goto www.rxlist.com and do a search. they def arent e ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

After finishing a synth of E, you have an oil left over that is then crystallized. I wont goto into specifics here, but if you would like to know further just pm me. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

From everything I have read and studied on the effects of E there should be no reason to worry about it counter-acting your birth control. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Liquid E is usually GHB. Thats the name they give it, to sell it. If you were to actually get liquid E it would be an oil. Hope this helps ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

ok well i actually tried it today, just to see if possibly there was any truth to what he was saying. now i dont usually eat during the day so i didnt have to worry bout an empty stomach. so i then proceeded to pick up and 8th of kind bud from my good friend, and bring it home to eat it. now i figured 60 bucks wasnt alot to lose. followed his instructions perfectly. well its not 11pm I did this at 4pm and I havent felt anything yet. maybe there is something with his body chemistry, but i never have heard or seen anyone else get high trying it this way. if i was doing something wrong i would def like to know. so maybe one day me and you should sit down and eat a few buds ? ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 10-02-2000).]

its only possible for the weed to show up in your urine, if you inhaled the smoke either by first hand or second hand. just smelling it is not going to give you a positive. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

ok your right erowid.org and lycaeum.org are completely wrong. and my chermistry teacher was completely wrong too. its cos of people like you that people get the wrong ideas about drugs. anthonyp I am giving out factual information, so why dont you get a fucking life. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 10-02-2000).]

If you believe this guy your deserve to waste your weed. so please go ahead be my guest The active ingredients in cannabis are fat and alcohol soluble so they can be extracted and added to foodstuff entering the system through the digestive tract rather than through the lungs. This type of consumption of marijuana tend to be both slower and more efficient than smoking it. Further the noxious effects of consuming heated smoke are completely eliminated. For these reasons this is the favored method of marijuana consumption by many people. Eating Marijuana must be heated before being consumed to activate the cannabanoids so one cannot simply eat raw grass. The traditional method of eating it is to cook it in a brownie, especially when it is in the form of hashish, though it can be used in any number of things. The recommended method of eating marijuana is to saute it in butter or margarine over medium heat, then to strain the remaining solids out and use the butter to cook with. One can use this marijuana butter to make brownies, cook vegetables, or however else one might use butter to cook with, one can even spread it on a slice of bread. Many people will mix the the residual solids in with whatever they are cooking in hopes of making use of whatever cannabanoids might still be in them, but if done properly this in not generally valuable. A typical ratio for making the marijuana butter is one stick of butter to one eight of an ounce of marijuana, and headed for fifteen to twenty minutes. Drinking One may extract the active ingredients from marijuana using alcohol and then use this tincture to make a potent drink. The highest proof alcohol available should be used, preferably 190 proof grain alcohol, since the water in the alcohol will dissolve other chemicals in the marijuana that one wishes to avoid. Some suggest soaking the grass in warm water for a period to remove those chemicals but that presents a whole host of other and is not really recommended. One may simply place the marijuana into a bottle of grain alcohol and let the canabanoids leach out, but this takes 2-3 weeks of time. A faster method is to heat the alcohol to sub-boiling and stir in the marijuana. Great deal of care should be taken if this method is chosen as the alcohol is highly flammable. The resulting tincture, often called "Green Dragon", is a light to emerald green liquid, which can be drunk straight, but this is not recommended. Highly lauded is a drink of 3 parts lemon lime soda, 1 part green dragon and a dollop of honey served over ice. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 10-01-2000).]

Then goto http://www.pillreports.com or www.dancesafe.org ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

I have seen sonique spin once. She really gets into when she spins. I love watching her. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Verve as in GHB ? Verve is also another name for GHB ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

ludes suck ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

IF I had a million right now, I wouldnt be so in debt. Also wouldnt be worrying if i could afford to go out this wkend or if I could afford to get some mdma. I got a hundred can you turn that into thousand. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Too bad I didnt see this earlier. I have over 40,000 college papers. From Princeton, Harvard, MIT, Cal Tech. I could of probably helped you out. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Einstein, Carl Sagan, Stephen Hawkins ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

IQ: 168 Sat: 1600 But what do these scores really matter. Someone may be book smart, but what about life in general. I have seen some really intelligent people end up going nowhere cos they couldnt handle life. Or they were to up tight about it. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

well at the beginning of the yr, I had about 10 million. Then the stock in the startup I worked at tanked so I am down to nothing once again. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Oakenfold also spins that track in his live mix from Havanna Cuba ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Ok thats def Pete Tong I just listened to the essential mix. I dont remember the name of the track, but as I said above check out www.tracklistings.org PVD plays the 2hr of that mix ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

If thats the one I am thinking off thats not PVD in the beginning thats Pete Tong. Thats if it's Live at the Gallery Tunrmills. Check out www.tracklistings.org for a playlist ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....