e-tarded

do a search at www.maps.org ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Your right, There is no excuse really except I got them from a trusted friend who said they were good. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

my heartbeat could be seen through my chest. plus when i checked my pulse i could tell that it was way out of control same with my other friend. except she had a lot more difficulty in breathing ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

These pills were most like mda and speed. As i am writing this now I am still feeling some of the effects from the pills. We didnt test them cos they were bought from a good friend, who after finding out what happened all that he could say was that no one mentioned my name. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

from my experience these pills would of been mda. Some of the strongest shit i have ever seen. These pills were taken on friday and we are still feeling the effects from them today, even after going to the hospital. If i had to take a guess I would say they were mda, cut with speed. In the time I have been rolling I have never ever felt like this, or would i ever wanna feel like this. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

This pills are dangerous, me and two of my friends had to be rushed to the hospital friday night. Our heartrates were at 170 beats per min. The doctor told us if we had waited any longer we would of most likely been dead. We didnt mix these pills with any other drugs before you go asking. Secondly this is definitely not our first or second time trying pills. Like i said before I have never in my life gotten a pill this strong. Someone else that i know who took this pill, rolled off of it for more the 24 hrs, with periods of speediness and periods of hallucinations. Please watch out for these pills. This story is not bullshit if you wanna call the hospital ask me for the number and I will gladly give it to you ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

This pills are dangerous, me and two of my friends had to be rushed to the hospital friday night. Our heartrates were at 170 beats per min. The doctor told us if we had waited any longer we would of most likely been dead. We didnt mix these pills with any other drugs before you go asking. Secondly this is definitely not our first or second time trying pills. Like i said before I have never in my life gotten a pill this strong. Someone else that i know who took this pill, rolled off of it for more the 24 hrs, with periods of speediness and periods of hallucinations. Please watch out for these pills. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 11-20-2000).]

ketamine is in used both a veterinary and a human anesthetic. Ketamine is usually used in children, and not in adults.It is called "dissociative" in action, which means that the mind is "separated" from the body. In many cases, this separation results in profound hallucinations and the sensation of entering another reality. Due to its anaesthetic nature, K can produce wide ranging effects from different amounts. More Information Can Be Found At Erowid ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 11-16-2000).]

Try Gingko Biloba, 5-HTP and Ginseng. Also you might wanna try some anti-oxidants after rolling. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

House Music ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Well the first rave I ever remember going to was the Storm parties, back in the early 90's. Before that I don't know if there was really a rave scene in the states like there is now. I started rolling when I was 15, I am 23 now. So thats eight years that I have been rolling. Which is about the same time I started going to parties. mdma was sold in bars before it was outlawed in 1985. You could order it at the bar just like ordering a beer. I am sure the use of mdma was prevalent during the disco days. Normally a topic like this should be posted in NY or possibly music, but since we are dealing with early E usuage thats kewl ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

To tell you the truth I honestly don't know. I will look into it though for you. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

ummm actually it wasnt a copied article. It's a piece I put together from different references and resources. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Thanks Just to clarify I am in no way a substitute for medical advice from a doctor or licensed pharmacist. I am just a knowledgable crackhead. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

http://bbs.clubplanet.com/ubb/Forum19/HTML/000101.html ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Thats definitely a bad idea since beer and mdma and broken down by the same enzyme in your liver known as the CYP2D6 enzyme (pronounced "sip-two-dee-six"). If you take MDMA along with another drug that is metabolized by the CYP2D6 enzyme, they will both be metabolized much more slowly, as the same enzymes struggle to break down two drugs at the same time. I would assume one or two beers wouldnt not adversely affect someone, but you can never be too sure. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 11-14-2000).] [This message has been edited by e-tarded (edited 11-14-2000).]

Gamma-hydroxybutyric acid (GHB) is an intriguing, naturally-occurring, 4-carbon compound with a structure similar to gamma-aminobutyric acid (GABA). It is described as a neurotransmitter and as a regulator of energy metabolism. First synthesized in 1960, GHB initially was investigated as an anesthetic due to its rapid induction of deep coma with only minor cardiovascular and respiratory depressant effects. Its lack of analgesia and tendency to cause seizurelike activity soon dampened enthusiasm for its use. Purported to act as a fat-burner and growth hormone promoter, GHB enjoyed a resurgence in the late 1980s as a food supplement for body builders and dieters. The withdrawal of L-tryptophan from the market, a supplement with similar purported effects, spurred GHB use. Also used as a hallucinogenic, euphoric, and sleep aid, it was easily obtained at health food stores, gyms, and mail order outlets. This newfound popularity coincided with a rising tide of GHB-related morbidity that soon caught the attention of regional poison control centers. The FDA subsequently prohibited the sale and manufacture of GHB in 1990. Since then, GHB has continued to enjoy a more clandestine popularity as an illicit drug, particularly in the Southeast and Western US. It currently is prevalent in the dance music scene (at raves and nightclubs) as an alternative to Ecstasy and amphetamines and is often used in conjunction with alcohol. It has been implicated, with Rohipnol, as a "date rape" drug. GHB generally comes in pure powder form or mixed with water. Its highly-concentrated, street form is available as a liquid in small plastic bottles, the size and shape of hotel shampoo bottles. The bottles generally cost only $10 and usually contain about 10 "hits." GHB goes by many street names, including grievous bodily harm, scoop, liquid ecstasy, cherry meth, growth hormone booster, liquid x and Georgia homeboy. GHB is readily manufactured from its precursor, gamma-butyrolactone (also known as 2(3h)-furanose dihydro or GBL). GBL is a solvent found in floor cleaning products, nail polish, and super glue removers. Saponification of the lactone with sodium hydroxide in the form of lye results in nearly quantitative conversion. However, this method is not without its drawbacks. There are several case reports of caustic alkali ingestion from undissolved lye. GBL also undergoes conversion into GHB in-vivo (by an unknown mechanism) and, accordingly, is associated with many of the same symptoms. GBL presently is readily purchased over the Internet and at health food stores under several brand names, including Fire Water, Renewtrient, Revivarant or Revivarant G, Blue Nitro or Blue Nitro Vitality, GH Revitalizer, Gamma G, and Remforce. Several states have caught on to this practice and have banned these products. The FDA has issued a warning and notice requesting manufacturers to issue a recall of GBL-containing products on January 21, 1999. On January 28, 1999, the FDA issued a warning to consumers not to purchase or use GBL products. A ban of this product is imminent. In an effort to skirt FDA regulation, several manufacturers have begun marketing 1,4 butanediol (BD), a chemical structurally similar and in many cases clinically indistinguishable from GHB. The FDA has declared BD a Class I Health Hazard - a potentially life-threatening drug. GHB’s unique attributes do have some legitimate uses. In Europe it is still used as an anesthetic, for alcohol and opiate addiction therapy, and for narcolepsy therapy. Only this last indication is recognized by the U.S. FDA, which allows its use on an experimental basis in narcolepsy trials. Pathophysiology: GHB is found naturally in the CNS, with the highest concentrations in the basal ganglia. GHB binding sites are present in the cortex, midbrain, substantia nigra, basal ganglia and, most predominantly, in the hippocampus, where it appears to mediate intrinsic neurons. It also is found in the peripheral blood and readily crosses the blood-brain and placental barriers. It is rapidly absorbed after ingestion; it takes 20-30 minutes to reach a maximal plasma concentration after the ingestion of a 12.5 mg/kg dose and increases to 30-60 minutes with a dose of 50 mg/kg. The elimination half-life is 27 minutes and proceeds in a dose-dependent, saturable manner. Elimination is via expired carbon dioxide. The pharmacokinetics of GHB in alcoholics are similar to that of nonalcoholics, although the frequency of serious side effects are less in the alcoholics, suggesting a cross-tolerance between alcohol and GHB. Although readily detected in the urine and serum by gas chromatographic-mass spectrometric techniques,traditional hospital toxicology assays typically do not include GHB. CNS GHB has a myriad of neurological effects. It binds to GABA-B receptors in the brain, inhibits noradrenaline release in the hypothalamus and mediates the release of an opiatelike substance in the striatum. It produces a biphasic dopamine response, increasing release at high doses and inhibiting its release at lower doses. True to its body-building claims, it does show an increase in growth hormone in rats and in one small human study. However, no study has ever demonstrated weight loss or increased muscle growth. Although GHB traditionally has been considered a potent epileptogenic drug and has been noted to cause epileptiform electroencephalographs (EEGs) in animals, human studies have failed to demonstrate EEG changes associated with use. It is thought that a reemergence syndrome characterized by myoclonic jerks of the face and extremities may have been mistaken for evidence of seizures. CNS depression is the hallmark of GHB use. An oral dose of 10 mg/kg produces short-term amnesia and hypotonia and 20-30 mg/kg produces drowsiness and sleep. After the ingestion of approximately 50-70 mg/kg, profound hypnosis and then deep coma rapidly ensue. GHB rapidly initiates delta wave and REM sleep and produces moderate amnesia but does not produce analgesia or muscle relaxation. It decreases cerebral glucose metabolism and increases cerebral blood flow, yet reduces intracranial pressure. Myoclonic jerks and respiratory depression accompany the descent into anesthesia. A Glasgow Coma Score (GCS) of 3 is not uncommon. One peculiar characteristic of GHB toxicity, despite such profound CNS and respiratory depression, is that patients often demonstrate extreme combativeness and agitation. Several physicians have been surprised when the individual suddenly awakens during an intubation attempt. The coma usually lasts from 1-4 hours and spontaneously resolves. Those patients intubated for respiratory depression typically have a longer time to recovery, but extubation within 8-10 hours is common; extubation in the ED has been described. The resolution is characteristically rapid and usually accompanied by myoclonic jerks and agitation. Cardiovascular (CV) GHB has been noted to cause bradycardia, decreased systemic vascular resistance, and hypotension. Pain or atropine rapidly causes an increase in heart rate and blood pressure. Studies of GHB infusion in hypovolemic shock have demonstrated an increase in mean arterial pressure and cardiac output when compared to a normal saline infusion. GHB also has been noted to have antidysrhythmic properties. Other effects One particularly fascinating property of GHB is its ability to prevent cell damage. Several studies have shown a reduction in oxygen requirements and a subsequent reduction in hypoxic cell damage. The exact mechanism of this tissue protective effect is unknown; however, several effects have been noted, including reductions in lipid peroxidation, lipolysis, free radical production, and a dampening of the inflammatory response. It has also been shown to be protective in radiation exposure. Benefit has been noted in a wide range of organ systems and in dozens of conditions, including hemorrhagic shock, sepsis, CVA, mesenteric ischemia, organ transplant, and MI. It is this last entity that has received the greatest attention. GHB has been found consistently to improve outcomes, including mortality, in several animal MI trials. However, its benefit in human MI trials has not yet been confirmed. The combination of its cell-protective and anesthetic properties has made GHB a candidate in certain types of surgery. Predominantly European literature has described its use in emergency laparotomy for hemorrhagic shock, aortic surgery, operations involving heart bypass, cataract surgery, labor, and many others. Its shortcomings as an anesthetic have led to a decline in its use in favor of more effective anesthetics. CNS Neurologic effects can range from mild (eg, nystagmus, dizziness, ataxia) to severe (eg, coma, respiratory failure, apnea, death). Typically, the patient experiences a short period of euphoria followed by a rapid and profound decline in the level of consciousness. Seizurelike activity and myoclonus commonly are reported. Pulmonary Respiratory depression Decreased respiratory rate Apnea Gastrointestinal (GI) Nausea Vomiting Physical: CNS The typical GHB ingestion presents with a profoundly depressed level of consciousness. A recent study noted that two-thirds of patients present with a GCS of less than 9, with a full one-third presenting with a GCS of 3. One unique aspect of GHB-induced coma is sporadic violent agitation, usually accompanying stimuli such as intubation attempts. The coma typically resolves completely and rapidly after a period of 1-4 hours. Seizurelike movements and myoclonus are common, particularly when descending into unconsciousness or on reemergence. Cardiovascular (CV) Approximately 36% of ingestions are accompanied by bradycardia. The bradycardia appears to be related to the depressed level of consciousness and is easily reversed with atropine. Hypotension accompanies about 10% of GHB ingestions. This usually is associated with coingestion of GHB and alcohol or another drug and usually is mild. If not readily resolved by stimulation or atropine administration, another ingestion or coingestion must be considered. Pulmonary Respiratory depression, evidenced by bradypnea to frank apnea, often occurs. Decreased breath sounds and rales may indicate aspiration. Gastrointestinal (GI) Nausea and vomiting are common with GHB ingestion and often accompany reemergence from unconsciousness. Prehospital Care: Prehospital personnel can contribute a great deal to an accurate diagnosis by obtaining a history of ingestion from the patient, friends, and bystanders and securing evidence of potential GHB ingestion (small shampoo bottles). Prehospital care primarily is supportive. Attention should be paid first and foremost to airway management and breathing. Oxygen should be administered and a patent airway established. Aspiration and cervical spine precautions should be observed. IV access should be established if possible. Naloxone should be considered for all comatose patients with any respiratory compromise. This may not be beneficial for GHB ingestions but is not considered to be detrimental. Intubation in the field should be reserved for severe, refractory, respiratory compromise and attempted only by experienced personnel when the airway is at risk. Emergency Department Care: ED management of GHB overdose is primarily supportive. Airway patency and aspiration precautions are of paramount importance. Consideration should be given to gastric lavage and/or activated charcoal if coingestion is suspected. Cardiac monitoring is indicated, given the relative frequency with which arrhythmias and conduction deficits have been noted. These interventions are of a limited benefit in isolated GHB ingestions due to the small amounts usually ingested (from one-fourth of a teaspoon to 4 tablespoons) and because of the rapidity of absorption (usually 10-15 minutes). If gastric lavage is deemed appropriate, the patient should be intubated prior to lavage to prevent potential aspiration. Symptomatic bradycardia that is unresponsive to stimulation should be treated with atropine. Given the usually benign course and rapid recovery of uncomplicated GHB intoxications, a conservative approach to intubation has been suggested. However, certain conditions necessitate intubation. If the history of GHB ingestion is unreliable in the presence of severe respiratory depression, hypoxia, or in preparation for lavage, rapid-sequence intubation should be performed. A sedative usually is not required, but neuromuscular blockade is recommended to avert the paradoxical agitation common with GHB. The reversal of GHB-induced CNS depression is a controversial issue. Although physostigmine has been shown to reverse sedation in clinical trials, most experts presently believe that the risks of its use (eg, bradycardia, asystole, seizures) outweigh the benefits in most GHB ingestions and that it should be reserved for selected cases, if used at all. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

I have taken a decent amount of drugs. I have tried just about everything, but I have also done my research on every drug that is out there. Whether it be researching erowid or lycaeum or reading research papers from medical groups. I have also take a few course at college in regards to pharmacology and chemistry. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Generally if you are following one of the recipes from erowid. Use a half ounce of weed. Alot of good receipes can be found on www.yahooka.com also ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Yea the Ld50 for pma supposedly starts at 50mg. Fucking chemists out looking to make a quicker buck. If they are really trying to save money, then they should make mda. I mean it is a couple of steps easier then synthesizing mdma. Or just raise their price a few pennies. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Well in the US at last count the Government had 3 dogs that were able to detect the smell of mdma. It may have changed, but still there is no reason to worry bout sending stuff through the mail. As long as the person doesn't go bragging to everybody and their mother. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

*raises hand* ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

its possible that they are, they could have some fillers in them. ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

They are mostly likely brown, cos they were not washed with acetone, before being pressed into a pill. mdma is actually a brownish substance, then is washed with acetone which produces the white powder ------------------ ~*P*L*U*R*~ Four Simple Words To Live By....

Powdered mdma is no worse then pills. Most likely even better since there will be no fillers or adulterants if you are getting it from a trusted source. Threshhold 30 mg Optimal for small or sensitive people 50 - 75 mg Optimal for most people 75 - 125 mg Optimal for large or un-sensitive people 125 - 175 mg Required by few (side effects increase) 200 + mg LD50 (Lethal Dose*) 106 mg/kg or ~6,000 mg ------------------ ~*P*L*U*R*~ Four Simple Words To Live By.... [This message has been edited by e-tarded (edited 11-08-2000).]